Objective To analyze the effects of dagliflozin treatment applied to type 2 diabetes mellitus in terms of lipid metabolism and visceral fat. Methods A retrospective analysis of 80 patients with type 2 diabetes treated from May 2023 to Songyuan Hospital of Integrated Chinese and Western Medicine, Jilin Province in May 2024, were divided into two groups with 40 cases each groups according to the different treatment methods. The reference group received conventional treatment, and the study group received dagliflozin treatment, and examined the two groups' blood glucose index, lipid metabolism index and visceral fat index. Results After the treatment, glycosylated hemoglobin, fasting blood glucose and 2 hours postprandial blood glucose were lower than before the same group, and the study group was lower than the reference group (P<0.05). After treatment, triglycerides, total cholesterol and LDL cholesterol were lower than before the same group, and the study group was lower than the reference group (P<0.05). After treatment, visceral fat index, visceral fatin, visceral adipose tissue-derived serine protease inhibitors were lower than before treatment in the same group, and the study group was lower than the reference group (P<0.05). Conclusions Dagagliflozin treatment for type 2 diabetes can improve fat metabolism, reduce visceral fat and have high application value.
Key words
Type 2 diabetes mellitus /
Dagliflozin /
Lipid metabolism /
Visceral fat
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
References
[1] 刘美,冯雪茹,刘梅林. 达格列净对冠心病合并2型糖尿病患者心外膜脂肪衰减值的影响[J]. 中国临床药理学杂志,2024,40(9):1243-1247.
[2] 陈小翠,周望,王艺霖,等. 胰岛素强化治疗联合达格列净治疗老年初诊2型糖尿病效果及安全性[J]. 中国老年学杂志,2024,44(8):1800-1803.
[3] 江煜旻,黄岚,冯涛. 达格列净对老年2型糖尿病合并射血分数保留型心力衰竭患者心、肾功能的影响[J]. 西北药学杂志,2024,39(3):110-114.
[4] 冯舒雅,任常谕,周后凤,等. 达格列净改善2型糖尿病患者肾血管功能、主动脉硬化和血管内皮功能障碍的研究[J]. 中国医院用药评价与分析,2024,24(4):435-438.
[5] 中国老年2型糖尿病防治临床指南编写组,中国老年医学学会老年内分泌代谢分会,中国老年保健医学研究会老年内分泌与代谢分会,等. 中国老年2型糖尿病防治临床指南(2022年版)[J]. 中华内科杂志,2022,61(1):12-50.
[6] 苏建培,王永丽,王志敏,等. 达格列净对老年射血分数保留型心力衰竭合并2型糖尿病患者炎症细胞因子及心功能的影响[J]. 实用临床医药杂志,2024,28(7):85-89,95.
[7] 洪冠宇,纪春敏,刘加河. 达格列净联合胰高血糖素样肽-1受体激动剂对2型糖尿病的疗效研究[J]. 实用临床医药杂志,2024,28(7):90-95.
[8] 赵志强,张梦遥,吕晓蕾,等. 达格列净联合常规治疗对2型糖尿病伴心力衰竭患者的心血管保护作用及对血清炎症因子和sST2水平的影响[J]. 临床和实验医学杂志,2024,23(9):914-918.
[9] 吴立华,黄达,冯青春. 利拉鲁肽联合达格列净治疗血糖控制不佳的老年2型糖尿病的疗效[J]. 中国老年学杂志,2023,43(11):2588-2592.
[10] 骆景耀,胡义阳. 达格列净治疗2型糖尿病的临床效果及对脂代谢和内脏脂肪的影响[J]. 临床合理用药,2023,16(20):31-33,37.