目的 本研究旨在讨论血常规检验中,高血脂患者乳糜血对血常规检验结果产生的影响。方法 本研究随机纳入2022年1月至2024年1月在本院接受治疗的高血脂症患者,40例,记作试验组,另外选用同期在本院接受血常规体检的健康受检者作为受试者,40例,记作对照组,共计80例,对比两组患者血液经过血浆置换后,各项指标与置换前的差异。结果 试验组血液样本经过血浆置换后,平均红细胞体积、红细胞比容、红细胞计数3项指标与血浆置换前比较无统计学意义（P>0.05）;血红蛋白、平均血红蛋白量、平均血红蛋白浓度、血小板计数、白细胞计数以及平均血小板体积相较于血浆置换前更低,中性粒细胞相比置换前更高（P<0.05）。对照组受检者血液样本接受置换后与置换前比较无统计学意义（P>0.05）。结论 血常规检验中,高血脂患者乳糜血样本严重影响检测结果。建议先对样本进行血浆置换后,再进行检测,可有效提高检测的精确度,为相关诊断与治疗提供数据参考。

Objective This study aims to discuss the impact of chyle blood on the results of blood routine tests in patients with hyperlipidemia. Methods This study randomly included 40 hyperlipidemia patients who received treatment in our hospital from January 2022 to January 2024 and were recorded as the trial group. In addition, 40 healthy subjects who underwent blood routine examinations at our hospital during the same period were selected as the control group, with a total of 80 subjects. The differences in various indicators between the two groups of patients after plasma exchange and before exchange were compared. Results The results of this study showed that the average red blood cell volume, hematocrit, and red blood cell count of the trial group's blood samples after plasma exchange were not statistically significant before plasma exchange (P>0.05). Hemoglobin, mean hemoglobin level, mean hemoglobin concentration, platelet count, white blood cell count, and mean platelet volume were lower compared to before plasma exchange, while neutrophils were higher compared to before exchange (P<0.05). There was no significant difference between the blood samples of the control group after replacement and before replacement (P>0.05). Conclusions In blood routine tests, chyle blood samples from patients with hyperlipidemia seriously affect the test results. It is recommended to perform plasma exchange on the sample before testing, which can effectively improve the accuracy of the detection and provide data reference for relevant diagnosis and treatment.