目的 分析磁共振(MR)弥散张量成像(DTI)在鉴别诊断颅内肿瘤中的价值。方法 选取陆军第七十三集团军医院在2023年5月至2024年5月接收的70例经病理检查证实的颅内肿瘤患者,分别开展常规MR与DTI扫描,评定下列指标在鉴别良、恶性肿瘤及诊断不同级别脑胶质瘤中的具体效能:相对表观扩散系数(rADC);各向异性分数(FA);自动生成表观扩散系数(ADC);相对各向异性分数(rFA)。结果 在70例患者中,良性30例、恶性40例,高、低级别脑胶质瘤分别为13例、27例。恶性肿瘤患者rFA、FA与ADC值均低于良性组(P<0.05)。绘制受试者工作特征(ROC)曲线,得知rFA+FA+ADC对恶性肿瘤进行诊断的曲线下面积(AUC)是0.986,高于单一指标;且对高级别脑胶质瘤进行诊断的AUC为0.907,亦高于单项指标检测,诊断价值更高。结论 MR DTI在鉴别诊断颅内肿瘤良恶性及对脑胶质瘤进行病理分级中,具有较好的应用价值。
Abstract
Objective To analyze the value of magnetic resonance (MR) diffusion tensor imaging (DTI) in the differential diagnosis of intracranial tumors. Methods Seventy patients with intracranial tumors confirmed by pathological examination were selected from the 73rd Group Army Hospital of the Army between May 2023 and May 2024. Routine MR and DTI scans were performed to evaluate the specific efficacy of the following indicators in distinguishing benign and malignant tumors and diagnosing different grades of gliomas: Relative apparent diffusion coefficient (rADC). Anisotropy score (FA). Automatically generate apparent diffusion coefficient (ADC). Relative anisotropy score (rFA). Results Among the 70 patients, there were 30 benign and 40 malignant cases, with 13 and 27 cases of high-grade and low-grade gliomas, respectively. The rFA, FA, and ADC values in patients with malignant tumors were lower than those in the benign group (P<0.05). Drawing the Receiver Operating Characteristic (ROC) curve, it was found that the area under the curve (AUC) of rFA+FA+ADC for diagnosing malignant tumors was 0.986, which was higher than that of a single indicator; And the AUC for diagnosing high-grade gliomas is 0.907, which is also higher than the detection of single indicators and has higher diagnostic value. Conclusions MR DTI has good application value in the differential diagnosis of benign and malignant intracranial tumors and the pathological grading of gliomas.
关键词
磁共振 /
颅内肿瘤 /
弥散张量成像 /
鉴别诊断
Key words
Magnetic resonance imaging /
Intracranial tumors /
Diffusion tensor imaging /
Differential diagnosis
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