血浆纤维蛋白原、血小板计数及D-二聚体检验对预测产后出血的价值

庄远丽

中国医药指南 ›› 2025, Vol. 23 ›› Issue (12) : 32-35.

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PDF(586 KB)
中国医药指南 ›› 2025, Vol. 23 ›› Issue (12) : 32-35. DOI: 10.15912/j.issn.1671-8194.2025.12.008
论著

血浆纤维蛋白原、血小板计数及D-二聚体检验对预测产后出血的价值

  • 庄远丽
作者信息 +

The Value of Plasma Fibrinogen, Platelet Count and D-Dimer Test in Predicting Postpartum Hemorrhage

  • ZHUANG Yuanli
Author information +

摘要

目的 分析血浆纤维蛋白原(FIB)、血小板计数(PLT)及D-二聚体(D-D)检验对预测产后出血的价值。方法 选取本院在2022年8月至2024年8月收治的70例产妇进行研究,根据其产后是否出现出血分为未出血组(n=42),出血组(n=28),给予FIB、PLT及D-D检验,分析其一般资料,对其相关数据进行Pearson分析。结果 出血组年龄(≥35岁)、产次(≥2次)、分娩方式(剖宫产)、妊娠并发症(有)、分娩孕周(<37周)、前置胎盘(有)、胎儿体重(≥4 000 g)、胎盘粘连(有)、胎盘早剥(有)均高于未出血组(P<0.05);两组产妇体重(≥23 kg/m2、<23 kg/m2)、受孕方法(自然受孕、辅助生殖技术)对比,差异无统计学意义(P>0.05);出血组FIB、PLT水平均低于未出血组(P<0.05);D-D水平高于未出血组(P<0.05);Pearson结果分析:FIB、PLT及D-D的AUC分别为0.882、0.884、0.834;联合检验在预测产后出血中的AUC为0.969;联合检验的AUC均高于单独检验的FIB、PLT及D-D水平(P<0.05);Logistic结果分析:以年龄、产次、分娩方式、妊娠并发症、分娩孕周、前置胎盘、胎儿体重、胎盘粘连、胎盘早剥、FIB、PLT、D-D为自变量,以产后出血为因变量;其中分娩方式、妊娠并发症、前置胎盘、胎儿体重、胎盘粘连、胎盘早剥、FIB、PLT均是造成产后出血的危险因素(P<0.05);D-D为保护因素(P<0.05)。结论 FIB、PLT及D-D在产后出血的预测中具有重要价值,且联合检测能显著提高预测准确性。

Abstract

Objective The value of plasma fibrinogen (FIB), platelet count (PLT) and D-dimer (D-D) test in predicting postpartum hemorrhage was analyzed. Methods A total of 70 parturients admitted to our hospital from August 2022 to August 2024 were selected for this study. According to whether postpartum hemorrhage occurred, they were divided into non-bleeding group (n=42) and bleeding group (n=28). FIB, PLT and D-D tests were given to analyze their general data, and Pearson analysis was performed on their related data. Results Age (≥35 years), delivery times (≥2 times), delivery mode (cesarean section), pregnancy complications (yes), gestational week (<37 weeks), placenta previa (yes), fetal body weight (≥4 000 g), placental adhesion (yes) and placental abruption (yes) in hemorrhage group were higher than those in non-hemorrhage group (P<0.05). There was no significant difference in body weight (≥23 kg/m2, <23 kg/m2) and conception method (natural conception, assisted reproductive technology) between the two groups (P>0.05). The levels of FIB and PLT in bleeding group were lower than those in non-bleeding group (P<0.05). The level of D-D was higher than that of non-bleeding group (P<0.05). The AUC of FIB, PLT and D-D were 0.882, 0.884 and 0.834, respectively. The AUC of combined test in predicting postpartum hemorrhage was 0.969. The levels of FIB, PLT and D-D of combined test were higher than those of single test (P<0.05). Logistic analysis of results: Age, delivery time, delivery mode, pregnancy complications, gestational weeks, placenta previa, fetal body mass, placental adhesion, placental abruption, FIB, PLT, D-D were independent variables, and postpartum hemorrhage was dependent variables. Delivery mode, pregnancy complications, placenta previa, fetal body mass, placental adhesion, placental abruption, FIB and PLT were all risk factors for postpartum hemorrhage (P<0.05). D-D was the protective factor (P<0.05). Conclusions FIB, PLT and D-D have important value in the prediction of postpartum hemorrhage, and the combined detection can significantly improve the prediction accuracy.

关键词

血浆纤维蛋白原 / 血小板计数 / D-二聚体 / 预测 / 产后出血

Key words

Plasma fibrinogen / Platelet count / D-dimer / Forecast / Postpartum hemorrhage

引用本文

导出引用
庄远丽. 血浆纤维蛋白原、血小板计数及D-二聚体检验对预测产后出血的价值[J]. 中国医药指南. 2025, 23(12): 32-35 https://doi.org/10.15912/j.issn.1671-8194.2025.12.008
ZHUANG Yuanli. The Value of Plasma Fibrinogen, Platelet Count and D-Dimer Test in Predicting Postpartum Hemorrhage[J]. Guide of China Medicine. 2025, 23(12): 32-35 https://doi.org/10.15912/j.issn.1671-8194.2025.12.008
中图分类号: R714.46+1   

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基金

泉州市科技计划项目(2016Z005)

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